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Albendazole solid dispersions against alveolar echinococcosis: a pharmacotechnical strategy to improve the efficacy of the drug
(Cambridge University Press, 2020-04)
Alveolar echinococcosis is a neglected parasitic zoonosis caused by Echinococcus multilocularis. The pharmacological treatment is based on albendazole (ABZ). However, the low water solubility of the drug produces a limited ...
Metformin improves the therapeutic efficacy of low-dose albendazole against experimental alveolar echinococcosis
(Cambridge University Press, 2022-01-21)
Alveolar echinococcosis (AE) is a severe disease caused by Echinococcus multilocularis. Its chemotherapeutic treatment is based on benzimidazoles, which are rarely curative and cause several adverse effects. Therefore, it ...
Albendazole nanocrystals in experimental alveolar echinococcosis: Enhanced chemoprophylactic and clinical efficacy in infected mice
(Elsevier Science, 2018-03-01)
Human alveolar echinococcosis is caused by the fox tapeworm Echinococcus multilocularis and is usually fatal if left untreated. Medical treatment with albendazole (ABZ) remains an effective option. However, due to its low ...
The combination of carvacrol and albendazole enhanced the efficacy of monotherapy in experimental alveolar echinococcosis
(Elsevier Science, 2021-10)
Alveolar echinococcosis is a helminthic zoonosis caused by the larval stage of Echinococcus multilocularis. When surgical resection of the parasite is not feasible, pharmacological treatment with albendazole is the only ...
In vivo activity of albendazole in combination with thymol against Echinococcus multilocularis
(Elsevier Science, 2015-09)
Human alveolar echinococcosis (AE) is caused by the fox tapeworm Echinococcus multilocularis and is usually lethal if left untreated. The current strategy for treating human AE is surgical resection of the parasite mass ...
Expression profiling of Echinococcus multilocularis miRNAs throughout metacestode development in vitro
(PLOS, 2021)
The neglected zoonotic disease alveolar echinococcosis (AE) is caused by the metacestode stage of the tapeworm parasite Echinococcus multilocularis. MicroRNAs (miRNAs) are small non-coding RNAs with a major role in regulating ...
Nuevas estrategias farmacoterapéuticas para el tratamiento de la neurocisticercosis y echinococcosis
(2019-03-28)
La neurocisticercosis (NCC), causada por el enquistamiento en el cerebro de larvas de Taenia solium y la echinococcosis, causada por la forma larval de parásitos del género Echinococcus, son enfermedades zoonóticas incluidas ...
O gênero Echinococcus no contexto de Saúde Única
(Universidade Federal de UberlândiaBrasilMedicina Veterinária, 2021)
Advances in the treatment, diagnosis, control and scientific understanding of taeniid cestode parasite infections over the past 50 years
(Elsevier, 2021)
In the past 50 years, enormous progress has been made in the diagnosis, treatment and control of taeniid cestode infections/diseases and in the scientific understanding thereof. Most interest in this group of parasites ...